Our Publications
Below are some of the key scientific publications underpinning our work. We build on over a decade of work conducted by our scientific founders and their groups.
Clicking “View Publication” redirects you to the publication at source.
Our Publications
Cell Therapy in Advanced Cirrhosis: From Preclinical Evidence to Clinical Application
Gastro Hep Advances
09/07/2026
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial
Nature Medicine
10/01/2025
Interpreting the new FDA draft potency guidance: an mRNA gene modified cell therapy perspective
Cell & Gene Therapy Insights
02/12/2024
EASL 2024 Late Breaker: Beneficial effects of autologous macrophage therapy on clinical outcomes in patients with compensated cirrhosis: extended follow-up data from a randomized controlled phase 2 trial
Journal of Hepatology
01/06/2024
EASL 2024 Poster: Developing a discovery platform for engineered macrophage cell therapies for end stage liver disease
Journal of Hepatology
01/06/2024
AASLD 2023 Poster: AN OPEN-LABEL PARALLEL-GROUP, PHASE II RANDOMISED CONTROLLED TRIAL OF AUTOLOGOUS MONOCYTE DERIVED MACROPHAGE INFUSION IN COMPENSATED CIRRHOSIS
AASLD Hepatology
13/11/2023
Study protocol: a multicentre, open-label, parallel-group, phase 2, randomised controlled trial of autologous macrophage therapy for liver cirrhosis (MATCH)
BMJ Open
08/11/2021
Liver regeneration and inflammation: from fundamental science to clinical applications
Nature Reviews
20/06/2021
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
AASLD Hepatology
23/03/2011
Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study
ISTC Cytotherapy
02/09/2015
Safety profile of autologous macrophage therapy for liver cirrhosis
Nature Medicine
07/10/2019
Cell therapy for advanced liver diseases: Repair or rebuild
Journal of Hepatology
22/09/2020