We offer an exciting opportunity for an experienced, committed individual to join our fast-growing team as a Financial Accounting Manager.

Reporting to the VP of Finance, the Financial Accounting Manager will:

• • Support the Vice President of Finance by leading the operational day to day elements involved with running an efficient, effective finance team.
• • Work with the Financial Planning & Analysis Manager to deliver excellence across the finance team, ensuring junior finance team members are managed and developed

Core responsibilities include:

Finance:

• • Maintenance of accurate and timely accounting records complying with internal and external reporting policies.
• • Preparation and analysis of monthly management accounts and data for the Board reporting pack as required by the Vice President of Finance, ensuring all records are processed within the month-end timetable
• • Oversight of day-to-day accounting activities including payroll.
• • Oversight and responsibility for monthly reconciliation of key control accounts including all bank reconciliations, aged debtors and creditors.
• • In conjunction with the FP&A Manager monitor and maintain a rolling cash flow forecast on a monthly basis.
• • To develop and have ownership of the Financial Procedures Manual ensuring it complies with the internal policies and external regulations and meets the needs of the Company providing appropriate levels of financial control.
• • To support the Vice President of Finance and FP&A Manager with the annual budget setting process.
• • To gather and prepare for submission financial data to enable timely completion of statutory returns.
• • To undertake termly finance staff appraisal and review meetings.
• • To liaise with external financial stakeholders – Auditors, HMRC, Bank, Payroll Provider
  

  Procurement:

• • Responsibility for all expenditure processes and the Amici procurement purchase ordering system.
• • Review of purchase orders to ensure purchasing procedures followed and goods are being ordered within agreed budgets.
• • Responsibility for the control and operation of payment processes, including the importing of weekly supplier BACS payments.
• • Regular meetings with designated budget holders.
  

  Payroll & Pensions:

• Overseeing the timely and accurate completion of the staff monthly payroll working with the external payroll provider as well as Inland Revenue and Pension provider
• Overseeing the financial administration of new starters, leavers along with monthly payroll contract changes.
• Checking of maternity & paternity requests and schedule information.
• Oversight and maintenance of accurate monthly staffing records.

Person Specification

Previous experience of working in a Biotech environment will be a distinct advantage and the successful candidate will have the right to work in the UK, and have the following qualification, skills and experience:

Qualifications:

 • Qualified Accountant with Financial Accounting & Reporting strengths

• • Can demonstrate continued professional development within Financial Accounting

Knowledge, Skills & Experience:

• • Intermediate/advanced excel skills
• • Working experience of SAGE accounting
• • Experience in leading or assisting in the review and implementation of financial accounting systems
• • Knowledge and experience of payroll for a staffing of above 50, using an external payroll bureau.
  • Proven track record of managing a transactional function through rapid growth and change
• • Excellent numeracy, literacy and financial data interpretation skills with an ability to recognise and question anomalies
• • Knowledge of budget setting and monitoring.
• • Keen problem solver who can focus on appropriate detail when solving problems and propose effective solutions

Other Personal Qualities:

• • Passion for our Company purpose
• • Ability to lead, to inspire, to work as part of a team, to work independently and to think laterally and creatively.
• • Excellent interpersonal & communication skills when working with colleagues at all levels and when interacting with external bodies

• Ability to communicate effectively with staff and external bodies at all levels.

Please direct any questions and CVs in the first instance to Harpreet Heir (harpreet@lifesciencepeople.co.uk) at Life Science People, our recruitment partners.

Due to continued high growth, in the company, we are seeking an experienced and confident accounts assistant to join our team.  The successful candidate will be comfortable communicating with all internal stakeholders including Management.

Assisting with all areas of accounting within the company, you will report directly to the Finance manager.

Main duties will include:
AMICI Procurement Finance User

• Adding and maintaining user access
• 3 way matching of PO, GRN and Invoice
• Data validation of invoice file prior to import to Sage 50
• Liaising with Amici support staff to resolve disputed issues

Sage 50 Purchase Ledger

• • Direct (Non-Amici) Purchase Invoice Checking
• • Direct Delivery note allocation
• • Coding and entering onto P/L System
• • Uploading electronic copies of invoices to Sage 50 system
• • Direct Invoice query letters/queries with suppliers
• • Payment runs and monthly reconciliation to Debtors Control Account

Sage 50 Nominal Ledger – to assist Finance Manager as required

• • Journal postings
• • Account analysis

Expense Claims and Credit Card Processing

• • Check and process employee expense claims on a timely basis as submitted, ensuring fully compliant with internal SOP, Company policies and HMRC requirements
• • Check and process employee credit card expenditure on a timely basis, ensuring fully compliant with internal SOP, Company policies and HMRC requirements
• • Resolve any issues arising from discrepancies in a timely manner

About you

• • HND in Accountancy/Finance related field or AAT/ACCA part qualified or equivalent
• • Proven advanced accounts preparation skills and experience
• • Experience in QuickBooks, Sage or Xero
• • An analytical mindset with strong numerical skills
• • Strong stakeholder management skills
• • Experienced IT user, particularly with Microsoft Office applications
• • Effective time management
• • Excellent organisational skills and ability to prioritise own working if a fast-paced environment

As an integral part of the team, you will be highly organised, with the ability to follow procedure and be able to multitask in a busy environment, moving between computer systems. An excellent communicator with good computer literacy, intermediate Excel user, you will be able to work to a high standard and ensure 100% accuracy.

Please direct any questions and CVs in the first instance to Harpreet Heir (harpreet@lifesciencepeople.co.uk) at Life Science People, our recruitment partners.

We are looking for a Clinical Project Manager to lead the planning and execution of clinical programs in adherence to ICH GCP, SOPs, FDA regulations, EU CTD/CTR and any other applicable regional or local guidelines.

Responsibilities

• • Preparation, design and/or review of essential documents for regulatory, ethics and other required local/national submissions;
• • Drive the identification and selection of clinical trial investigators as per clinical operations strategy;
• • Lead/assist in development of the protocol, amendments and related GxP documents;
• • Development of SOPs, Forms, guidelines and GxP training materials;
• • Organisation and management of various trial-related meetings e.g. investigator meeting, Advisory Board, Data Monitoring Committee, Steering Committee etc;
• • Maintenance of regulatory and local clinical trials databases/registries
• • Management and oversight of Contract Research Organisation/vendor management, as required
• • Development of Case Report Forms (CRFs), CRF completion guidelines, and associated documents in collaboration with data management and biostatistics groups;
• • Creation of study manuals to facilitate study oversight and management;
• • Point of contact for all site-related issues and procedural questions;
• • Cross-functional engagement with operational teams e.g. data management, drug supply management, clinical development, biostatistics, research, regulatory and quality;
• • Set-up and maintenance of Trial Master File (TMF), ensuring audit readiness of documentation at all times
• • Ensure study certifications, insurance, licenses and registrations are maintained;
• • Attend site visits (including, but not limited to, Site Initiation Visits, study surgeries) where local and national travel policies allow;

Experience

• • Bachelor degree or equivalent degree is required, with advanced degree preferred. At least one of the degrees in life science/healthcare is preferred.
• • 8-10 years of clinical development experience of this minimum 3-5 years working as a Clinical Project Manager in Phase I-IV studies within the pharmaceutical industry or a CRO
• • Demonstrable operational capabilities in all aspects of clinical trial related activities, and proven ability to meet timelines.
• • Ability to prioritise workload in a fast-paced environment
• • Excellent communication, organization and tracking skills.
• • Proven ability to work either independently or in a team setting
• • Proven networking skills and ability to share knowledge and experience amongst colleagues.
• • Profound knowledge of ICH/GCP; comprehensive knowledge of clinical trial design methodologies and understanding of the overall drug development process.
• • Basic knowledge of relevant therapeutic areas.
• • Travel up to 30%

Desirable

• • ATMP/GMO/Biologics handling
• • Previous monitoring experience
• • Immunology and/or hepatology experience

• Working within a small to mid-sized Biotech

Please direct any questions and CVs in the first instance to Harpreet Heir (harpreet@lifesciencepeople.co.uk) at Life Science People, our recruitment partners.

We are looking to recruit an Analytical Development scientist to join our fast-growing ‘Product Development and Supply’ team based in either London or Edinburgh! This position is a full-time opportunity, on a permanent basis. In this role you will drive the development and implementation of new analytical approaches for the characterisation of genetically engineered macrophages for therapeutic applications in liver cirrhosis. You will work collaboratively with internal teams and multiple external partners to deliver programs of work which will help bring these much-needed therapies to patients.

Key responsibilities:

We are seeking an experienced and highly motivated scientist to play a key role in the execution of analytical development programs for the Resolution Therapeutics product pipeline.

Key responsibilities include:

• Play a key role in the delivery of analytical development activities including the design and authorship of experimental plans and the production of scientific reports
• Independently execute scientific programmes of work in the laboratory while following quality procedures
• Analysis of analytical data including interpretation of results and assessment of impact on project delivery
• Presentation and reporting of analytical development activities to the wider project teams
• Applying experience and creativity to overcome research challenges including assay troubleshooting to ensure analytical approaches are fit-for-purpose
• Designing and supporting activities for assay qualification both internally and in-collaboration with our external partner sites
• Production of technology transfer documentation
• Supporting training programs for external partners to support technology transfer
• Contribute to the continual improvement of processes for data analysis, recording and reporting.

Requirements for the role:

The successful candidate must have the following:

• An MSc or PhD in a field related to cell therapies
• A minimum of 2 years industrial experience applying a range of analytical assays, preferably relating to cell therapy characterisation
• A high level of experience in molecular biology and/or flow cytometry techniques
• Experience of using cell-based assays
• Experience of assay development and optimisation
• Experience of data analysis and the use of statistical programmes
• Experience of the processes involved in the qualification/validation of analytical assays
• Experience of working within a team environment to deliver results
• Experience of authoring and following SOP’s
• Ability to take initiative and work independently
• Ability to maintain accurate and up to date records

The following is also desirable:

• A working knowledge of immunology and chronic inflammatory diseases, preferably chronic liver disease
• Experience of the processes involved in technology transfer
• Experience of working with a quality management system
• Experience of working with different primary cell types including stem cells

Benefits:
Our competitive package includes discretionary bonus, income protection, pension, private health insurance, and life assurance, as well as an opportunity to participate in the Company’s incentive shares scheme.

Please direct any questions and CVs in the first instance to Harpreet Heir (harpreet@lifesciencepeople.co.uk) at Life Science People, our recruitment partners.

We are looking to recruit an Analytical Development Group Leader to join our fast-growing ‘Product Development and Supply’ team based in London! This position is a full-time opportunity, on a permanent basis.

In this role you will drive the development and implementation of new analytical approaches for the characterisation of genetically engineered macrophages for therapeutic applications in liver cirrhosis. You will work collaboratively with internal teams and multiple external partners to deliver programs of work which will help bring these much-needed therapies to patients.

Key responsibilities:

Scientific leadership

We are seeking an experienced and highly motivated scientist to lead the execution of analytical development programs for the Resolution Therapeutics product pipeline. This role will include line management responsibility for the London based analytical team and matrix management across a range of different company functions.

Key responsibilities include:

• Overseeing delivery of analytical development activities including approval of experimental plans and the sign-off of reports
• Review and approval of analytical data and the implementation of new methods for data modelling and trending
• Presentation and reporting of analytical development activities to senior management and wider project teams
• Supporting the development of analytical strategies to improve product and process characterisation and to drive advances in QC product release testing
• Providing management and direction to laboratory staff for project activities, oversee daily operations to monitor quality and project timelines, and assist in preparation and implementation of company policies, quality systems and training programs.
• Resource management for the analytical team and prioritisation setting in-line with wider strategic objectives
• Playing a leading role in the continual improvement of processes for data analysis, recording and reporting.

Quantity & Regulatory support

Using your experience of cell therapy development and product characterisation you will contribute to the delivery of quality dossiers to support regulatory submission; this will include supporting:

• The compilation of Master Testing Strategies & QC profiles
• CMC & material risk assessments
• Identification and assessment of Critical Quality Attributes
• Compilation of dossiers for regulatory scientific advice

Technology transfer

The successful candidate will play a leading role in the transfer of products and processes to external partners to support GMP manufacturing. This will include:

• Designing and leading activities for assay qualification both internally and in-collaboration with our external partner sites
• Overseeing the production of technology transfer documentation in-line with quality principles
• Identifying and managing equipment purchases to allow assay transfer to QC
• Developing and managing training programs for external partners to support technology transfer
• Supporting the development of databases to record and analyse data from external partners

Requirements for the role:

The successful candidate must have the following:

• An MSc or PhD in a field related to cell therapies
• A minimum of 5 years industrial experience working in analytical development, preferably relating to cell therapy characterisation
• Proven experience in the development and qualification/validation of analytical assays
• Expert knowledge in molecular biology and/or flow cytometry techniques
• Experience of using cell-based assays for product characterisation
• Expert knowledge of analytical data analysis and the use of statistical programmes
• Experience of designing and implementing in-process control strategies to support cell therapy process development and/or GMP manufacturing
• Experience of working within a multidisciplinary team
• Experience of leading technology transfer activities to external sites
• An understanding of the regulatory and clinical processes involved during the cell therapy product lifecycle
• Experience of direct line management including goal setting and performing annual appraisals

The following is also desirable:

• Knowledge or experience in the application of different technologies used during cell therapy manufacturing
• Experience of activities and procedures required to manage a safe laboratory working environment
• Experience of working with a quality management system
• Experience of managing budgets and working to tight deadlines
• Experience or understanding of different primary cell types including stem cells

Benefits:

Our competitive package includes discretionary bonus, income protection, pension, private health insurance, and life assurance, as well as an opportunity to participate in the Company’s incentive shares scheme.

Please direct any questions and CVs in the first instance to Harpreet Heir (harpreet@lifesciencepeople.co.uk) at Life Science People, our recruitment partners.

We offer an exciting opportunity to join our fast-growing team as Director, Corporate Development. In this role you will participate in the company’s business development activities, including identification, negotiation and oversight of strategic partnerships.

Your responsibilities include:

• Identifying, scoping and proactively seeking partnerships and major supplier relationships for the company as needed to deliver the company’s strategy
• Leading negotiations and overall deal process around major partnerships, procurement arrangements
• Supporting the heads of R&D units on setting their respective strategy and long-term vision; overseeing strategic review exercises as required
• Contributing to the development of RTx’s Innovation Agenda by reviewing opportunity landscape, keeping up with new technology developments and working with the Head of IP on identify protectable areas for growth
• Overseeing and negotiating day-to-day legal contracts such as supplier agreements, confidential disclosure agreements, consultancy agreements and other operational agreements
• Responsible for analysing the global market of prospective companies to identify potential acquisition and partnership transactions in line with RTx’s strategic plan and innovation agenda
• Maintain industry-wide perspective on major trends and their implications for RTx. This includes competitive, technology, regulatory, distribution channel and macro-economic trends
• Track competitive landscape and carry out regular benchmarks to identify areas of opportunity
You will report directly to the VP, Corporate Development.
The successful candidate will have the right to work in the UK, and will have the following qualifications, skills, and experience:

Your Experience

Essential:

• An undergraduate degree, preferably up to at least Masters level in a scientific or engineering discipline
• 3-5 years’ experience at a top tier strategy consulting firm and/or in the biotechnology and pharmaceuticals industry
• Experience negotiating commercial partnerships and/or licensing agreements and/or major procurement deals; excellent negotiation skills
• Experience framing and modelling complex problems, making informed and reasonable assumptions and ultimately driving to a solution and recommendation
• Working knowledge of different types of commercial and legal agreements
• Excellent verbal, numerical and written communication skills
• Proficiency in preparing and presenting corporate documents for board-level audiences
• Self-starting, can-do attitude; comfort operating in a fast-paced uncertain environment
• Preferred – Experience working in a small company, preferably in the life sciences sector